标題：Novel magnetic-fluorescent CS-Fe3O4@ZnS:Mn/ZnS (core/shell) nanoparticles: Preparation, characterization and damage to bovine serum albumin under UV irradiation作者：Liu, Li; Xiao, Ling; Cao, Chunhua

來源出版物：MATERIALS CHEMISTRY AND PHYSICS 卷：140 期：2-3 頁：575-582 DOI：10.1016/j.matchemphys.2013.04.007 出版年：JUL 15 2013

摘要： Novel magnetic-fluorescent nanoparticles (CS-Fe3O4@ZnS:Mn/ZnS) combined ZnS:Mn/ZnS semiconductor nanoparticles and Fe3O4 magnetic nanoparticles with chitosan (CS) matrix were prepared and characterized. Characterization results indicate that CS-Fe3O4@ZnS:Mn/ZnS (core/shell) nanoparticles show superparamagnetic and strong fluorescent properties. Introduction of ZnS shell significantly enhances the photoluminescence intensity by 3.5 times. The saturation magnetization of CS-Fe3O4@ZnS:Mn/ZnS nanoparticles was 14.85 emu g(-1) at room temperature. The interaction and damage of CS-Fe3O4@ZnS:Mn/ZnS to bovine serum albumin (BSA) under UV irradiation was investigated by ultraviolet visible and fluorescence spectra. The results show that electrostatic interaction is the major force for the binding processes of BSA to the surface of CS-Fe3O4@ZnS:Mn/ZnS. The damage of BSA is prone to happen in the presence of CS-Fe3O4@ZnS:Mn/ZnS under UV irradiation. CS-Fe3O4@ZnS:Mn/ZnS may be potential candidate for application as photosensitizers in photodynamic therapy, and fluorescence imaging and magnetic resonance imaging contrast agents for theranostics of cancer.

入藏号：WOS:000320837700023

文獻類型：Article

語種：English

作者關鍵詞：Biomaterials, Magnetic materials, Composite materials, Interfaces

擴展關鍵詞：SHELL QUANTUM DOTS; SONODYNAMIC DAMAGE; PROTEIN; BSA; PHOTOLUMINESCENCE; ENHANCEMENT; ADSORPTION; KINETICS; THERAPY

通訊作者地址：肖玲(Xiao, Ling);Wuhan Univ, Coll Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430072, Hubei Province, Peoples R China.

電子郵件地址：liuli5058@yahoo.cn; 775706196@qq.com

地址：

[Liu, Li; Xiao, Ling; Cao, Chunhua] Wuhan Univ, Coll Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430072, Hubei Province, Peoples R China.

研究方向：Materials Science

ISSN：0254-0584