标題：Mechanism of photocatalytic oxidation of guanine by BiOBr under UV irradiation作者：Hou, Haobo; Wang, Xiaoxing; Chen, Chuncheng; Johnson, David M.; Fang,Yanfen; Huang, Yingping

來源出版物：CATALYSIS COMMUNICATIONS卷：48頁：65-68 DOI：10.1016/j.catcom.2014.01.023 出版年：MAR 10 2014

摘要：This article analyzes the mechanism details of guanine photocatalytic oxidation on the surface of BiOBr nanopartides under UV irradiation. The reaction of O-2(.)- with radical species, generated from primary oxidation of guanine by hole, is proposed to be the dominant cause of guanine damage. The present work demonstrates that Bi0Br photocatalysis provided good model to investigate the reaction of substrate radical with the in situ formed O-2(.)-. It also implicates that the frequently-used biomarker for DNA damage 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG) may be ineffective in the situation that damage is caused by O-2(.-).

入藏号：WOS:000333999200015

文獻類型：Article

語種：English

作者關鍵詞：Guanine base, Oxidative damage, Photocatalysis, Mechanism

擴展關鍵詞：DNA-DAMAGE; CELLS; BIOMARKER; 8-OHDG; TIO2

通訊作者地址：Chen, Chuncheng; China Three Gorges Univ, Collaborat Innovat Ctr Geo Hazards & Ecoenvironm, Yichang 443002, Hubei, Peoples R China.

地址：

[Hou, Haobo; Wang, Xiaoxing; Huang, Yingping] Wuhan Univ, Sch Resource & Environm Sci, Wuhan 430072, Hubei, Peoples R China.

[Wang, Xiaoxing; Chen, Chuncheng; Johnson, David M.; Fang, Yanfen; Huang, Yingping]China Three Gorges Univ, Collaborat Innovat Ctr Geo Hazards & Ecoenvironm, Yichang 443002, Hubei, Peoples R China.

[Wang, Xiaoxing; Chen, Chuncheng; Johnson, David M.; Fang, Yanfen; Huang, Yingping] China Three Gorges Univ, Minist Educ, Engn Res Ctr Ecoenvironm Three Gorges Reservoir R, Yichang 443002, Hubei, Peoples R China.

研究方向：Chemistry

ISSN：1566-7367